Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer cell line MCF-7

Synergistic antitumor effect of TRAIL and adriamycin on the human breast cancer cell line MCF-7

The aim of the present study was to determine the effect of the combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and adriamycin (ADM) on the human breast cancer cell line MCF-7 and to identify potential mechanisms of apoptosis. Cell viability was analyzed by the MTT ass...

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Bibliographic Details
Main Authors: D.D. Cui, Y. Huang, S.H. Mao, S.C. Chen, M. Qiu, L.L. Ji, C. Yi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2009-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
TRAIL
TRAIL receptors
Breast cancer
Adriamycin
Apoptosis
Synergism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000900013

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