Functional Detection of TNF Receptor Family Members by Affinity-Labeled Ligands

Abstract Aberrant expression of TNF family of cytokines has been linked to human diseases, and biologics targeting their signaling have become the best selling drugs globally. However, functional detection with labeled ligands for accurate detection of TNFR family of receptor-expressing target tissu...

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Bibliographic Details
Main Authors: Yang Xu, Lingmo Chang, Anliang Huang, Xiaojun Liu, Xinyu Liu, Hong Zhou, Joshua G. Liang, Peng Liang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06343-4