Emerging ensembles of kinetic parameters to characterize observed metabolic phenotypes

Emerging ensembles of kinetic parameters to characterize observed metabolic phenotypes

Abstract Background Determining the value of kinetic constants for a metabolic system in the exact physiological conditions is an extremely hard task. However, this kind of information is of pivotal relevance to effectively simulate a biological phenomenon as complex as metabolism. Results To overco...

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Bibliographic Details
Main Authors: Riccardo Colombo, Chiara Damiani, David Gilbert, Monika Heiner, Giancarlo Mauri, Dario Pescini
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Bioinformatics
Subjects:
Ensembles
Fluxes
Kinetic parameters
Mechanistic simulations
Metabolism
ODEs
Online Access:http://link.springer.com/article/10.1186/s12859-018-2181-7

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