Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

<p>Abstract</p> <p>Background</p> <p>Asthma is a chronic inflammatory airway disease influenced by genetic and environmental factors that affects ~300 million people worldwide, leading to ~250,000 deaths annually. Glucocorticoids (GCs) are well-known therapeutics that a...

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Bibliographic Details
Main Authors: Diez Diego, Goto Susumu, Fahy John V, Erle David J, Woodruff Prescott G, Wheelock Åsa M, Wheelock Craig E
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Genomics
Subjects:
Asthma
Inflammation
Glucocorticoids
Fluticasone propionate
Flovent
Network analysis
PPAR pathway
Toll-like receptor pathway
Interferon pathway
Online Access:http://www.biomedcentral.com/1755-8794/5/27

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