Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study

Paracetamol clinical dosing routine leads to paracetamol underexposure in an adult severely ill sub-Saharan African hospital population: a drug concentration measurement study

Abstract Background Hospitals in sub-Saharan Africa (SSA) continue to receive high numbers of severely ill (HIV-infected) patients with physical pain that may suffer from hepatic and renal dysfunction. Paracetamol is widely used for pain relief in this setting but it is unknown whether therapeutic d...

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Bibliographic Details
Main Authors: Jeannet C. Bos, Mabor C. Mistício, Ginto Nunguiane, Ron A. A. Mathôt, Reinier M. van Hest, Jan M. Prins
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Research Notes
Subjects:
Paracetamol
Palliative care
Africa south of the Sahara
Hospital
Oral drug administration
Pharmacokinetics
Online Access:http://link.springer.com/article/10.1186/s13104-017-3016-8

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