Utilization of Enzyme-Immobilized Mesoporous Silica Nanocontainers (IBN-4) in Prodrug-Activated Cancer Theranostics

Utilization of Enzyme-Immobilized Mesoporous Silica Nanocontainers (IBN-4) in Prodrug-Activated Cancer Theranostics

To develop a carrier for use in enzyme prodrug therapy, Horseradish peroxidase (HRP) was immobilized onto mesoporous silica nanoparticles (IBN-4: Institute of Bioengineering and Nanotechnology), where the nanoparticle surfaces were functionalized with 3-aminopropyltrimethoxysilane and further conjug...

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Bibliographic Details
Main Authors: Bau-Yen Hung, Yaswanth Kuthati, Ranjith Kumar Kankala, Shravankumar Kankala, Jin-Pei Deng, Chen-Lun Liu, Chia-Hung Lee
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Nanomaterials
Subjects:
mesoporous silica nanoparticles
enzyme immobilization
Institute of Bioengineering and Nanotechnology (IBN-4)
anti-cancer
prodrug therapy
Online Access:http://www.mdpi.com/2079-4991/5/4/2169

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