Cyclin G2 Inhibits Oral Squamous Cell Carcinoma Growth and Metastasis by Binding to IGFBP3 and Regulating the FAK-SRC-STAT Signaling Pathway

Cyclin G2 Inhibits Oral Squamous Cell Carcinoma Growth and Metastasis by Binding to IGFBP3 and Regulating the FAK-SRC-STAT Signaling Pathway

The cell cycle protein cyclin G2 is considered a tumor suppressor. However, its regulatory effects and potential mechanisms in oral cancers are not well understood. This study aimed to investigate the effect of cyclin G2 on oral squamous cell carcinoma (OSCC). The data from 80 patients with OSCC wer...

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Bibliographic Details
Main Authors: Danning Wang, Jinlan Gao, Chenyang Zhao, Sen Li, Di Zhang, Xiaoyu Hou, Xinbin Zhuang, Qi Liu, Yang Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
cell cycle protein cyclin G2
oral squamous cell carcinoma
tumor suppressor
insulin-like growth factor binding protein 3
integrin
focal adhesion kinase
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.560572/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.560572/full

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