Endocrine pancreatic development: impact of obesity and diet

During embryonic development, multipotent endodermal cells differentiate to form the pancreas. Islet cell clusters arising from the pancreatic bud form the acini tissue and exocrine ducts whilst pancreatic islets form around the edges of the clusters. The successive steps of islet differentiation ar...

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Bibliographic Details
Main Authors: Jacqueline F O'Dowd, Claire Joanne Stocker
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00170/full