Mitochondria-Associated endoplasmic reticulum Membranes (MAMs) microenvironment: targeting autophagic and apoptotic pathways in cancer therapy

Mitochondria-Associated endoplasmic reticulum Membranes (MAMs) microenvironment: targeting autophagic and apoptotic pathways in cancer therapy

Autophagy is a tightly regulated catabolic pathway that terminates in the lysosomal compartment after the formation of a cytoplasmic vacuole that engulfs macromolecules and organelles. Notably, autophagy is associated with several human pathophysiological conditions, playing either a cytoprotective...

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Bibliographic Details
Main Authors: Simone ePatergnani, Sonia eMissiroli, Saverio eMarchi, Carlotta eGiorgi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Autophagy
Cell Death
Cancer
mam
Calcium (Ca2+)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00173/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00173/full

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