Dynamic association between AT(N) profile and cognition mediated by cortical thickness in Alzheimer’s continuum

Dynamic association between AT(N) profile and cognition mediated by cortical thickness in Alzheimer’s continuum

Background: The recently-proposed National Institute on Aging and Alzheimer’s Association research framework organizes Alzheimer’s disease (AD) biomarkers based on amyloid/tau/neurodegeneration (AT(N)). This study investigated the mediating effect of structural change in brain MRI on changes in cogn...

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Bibliographic Details
Main Authors: Jae-Won Jang, Yeshin Kim, Seongheon Kim, Sang Won Park, Sung Ok Kwon, Young Ho Park, Jae-Sung Lim, Young Chul Youn, Sung Hun Kim, SangYun Kim
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Mild cognitive impairment
Alzheimer’s disease
CSF biomarkers
Brain MRI
Beta amyloid
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220301194

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http://www.sciencedirect.com/science/article/pii/S2213158220301194

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