The bioenergetics of integrin-based adhesion, from single molecule dynamics to stability of macromolecular complexes

The forces actively generated by motile cells must be transmitted to their environment in a spatiotemporally regulated manner, in order to produce directional cellular motion. This task is accomplished through integrin-based adhesions, large macromolecular complexes that link the actin-cytoskelton i...

Full description

Bibliographic Details
Main Authors: Laurent MacKay, Anmar Khadra
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019304970