The pathological diagnostic of bronchial glands cancer.

• Main Authors: Gasyuk A.P., Royko N.V., Curilko Y.V.
• Format: Article
• Language: Russian
• Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2007-01-01
• Series: Морфологія
• Subjects: bronchial glands cancer; histochemistry; goblet cells; transitional cellular epithelium; cylinder epithelium
• Online Access: http://www.morphology.dp.ua/_pub/MORPHO-2007-01-01/07gaprbz.pdf

The purpose of study was the determination of histological variants of bronchial glands cancer depending on the caliber of bronchi. The resected lungs of patients with bronchogenic cancer were used. The histological sections were stained by hematoxilin-eosin and Van Hyzon, the histochemical reaction for elastic elements by Hart, Shiff-alcian blue, Bergman and for fibrin by Mallory was carried. The fragments of principal, lobar, segmental, intrasegmental and lobular bronchi were used. The bronchial glands at mucoepidermal cancer were represented mainly by goblet cells, the mucus was inside of bronchial tubes with the admixtures of leucocytes, cells were partly substituted by transitional cellular epithelium that reminds multilayers flat epithelium. The cancer of gland ducts was characterized, saving the cylinder epithelium, by presence of lymphoid cell accumulations. The acinar variant of cancer of bronchial glands on the histological structure was characterized by the presence of two types: glomerular and small cystic. Our data suggest that the cancer of bronchial glands clinically demonstrates the local destructive growth, is located around the bronchial tubes and simulates flat cellular cancer. The offered complex of histological and histochemical methods, and also carried comparisons of structure of bronchial glands, allows differentiating more details in the type of cancer.