BD-Func: a streamlined algorithm for predicting activation and inhibition of pathways
BD-Func (BiDirectional FUNCtional enrichment) is an algorithm that calculates functional enrichment by comparing lists of pre-defined genes that are known to be activated versus inhibited in a pathway or by a regulatory molecule. This paper shows that BD-Func can correctly predict cell line alternat...
Main Authors: | Charles D. Warden, Noriko Kanaya, Shiuan Chen, Yate-Ching Yuan |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-09-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/159.pdf |
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