BD-Func: a streamlined algorithm for predicting activation and inhibition of pathways

BD-Func (BiDirectional FUNCtional enrichment) is an algorithm that calculates functional enrichment by comparing lists of pre-defined genes that are known to be activated versus inhibited in a pathway or by a regulatory molecule. This paper shows that BD-Func can correctly predict cell line alternat...

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Bibliographic Details
Main Authors: Charles D. Warden, Noriko Kanaya, Shiuan Chen, Yate-Ching Yuan
Format: Article
Language:English
Published: PeerJ Inc. 2013-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/159.pdf