Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord.

Acute colitis induces neurokinin 1 receptor internalization in the rat lumbosacral spinal cord.

Substance P (SP) and its receptor, the neurokinin 1 receptor (NK1R), play important roles in transmitting and regulating somatosensory nociceptive information. However, their roles in visceral nociceptive transmission and regulation remain to be elucidated. In the previous study, moderate SP immunor...

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Bibliographic Details
Main Authors: Ming-Ming Zhang, Wei Ji, Li-Yu Pei, Wen Wang, Tao Chen, Wei Wang, Hui Li, Ting Zhang, Sheng-Xi Wu, Yun-Qing Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3605455?pdf=render

Internet

http://europepmc.org/articles/PMC3605455?pdf=render

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