Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro

Abstract.: The thienopyridine derivative ticlopidine (TCL) is an inhibitor of adenosine diphosphate-induced platelet aggregation. Combination therapy with a thienopyridine derivative and aspirin is standard after coronary stenting, although more hemorrhagic complications occur with the combination t...

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Bibliographic Details
Main Authors: Yuichi Kinoshita, Naoki Matsumoto, Minoru Watanabe, Yuko Takeba, Yutoku Yoshida, Keiichiro Ohba, Satoshi Suzuki, Fumio Itoh, Toshio Kumai, Shinichi Kobayashi
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319306565