Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite

Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite

Ni/NiO nanoflower modified reduced graphene oxide (rGO) nanocomposite (Ni/NiO-rGO) was introduced to screen printed electrode (SPE) for the construction of a nonenzymatic electrochemical glucose biosensor. The Ni/NiO-rGO nanocomposite was synthesized by an in situ reduction process. Graphene oxide (...

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Main Authors: Xiaohui Zhang, Zheng Zhang, Qingliang Liao, Shuo Liu, Zhuo Kang, Yue Zhang
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Sensors
Subjects:
nonenzymatic
glucose
graphene
biosensor
in situ
Online Access:http://www.mdpi.com/1424-8220/16/11/1791
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spelling doaj-4c748f2f59db48f39dd15223599206952020-11-24T23:02:35ZengMDPI AGSensors1424-82202016-10-011611179110.3390/s16111791s16111791Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene NanocompositeXiaohui Zhang0Zheng Zhang1Qingliang Liao2Shuo Liu3Zhuo Kang4Yue Zhang5State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaState Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaState Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaState Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaState Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaState Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaNi/NiO nanoflower modified reduced graphene oxide (rGO) nanocomposite (Ni/NiO-rGO) was introduced to screen printed electrode (SPE) for the construction of a nonenzymatic electrochemical glucose biosensor. The Ni/NiO-rGO nanocomposite was synthesized by an in situ reduction process. Graphene oxide (GO) hybrid Nafion sheets first chemical adsorbed Ni ions and assembled on the SPE. Subsequently, GO and Ni ions were reduced by hydrazine hydrate. The electrochemical properties of such a Ni/NiO-rGO modified SPE were carefully investigated. It showed a high activity for electrocatalytic oxidation of glucose in alkaline medium. The proposed nonenzymatic sensor can be utilized for quantification of glucose with a wide linear range from 29.9 μM to 6.44 mM (R = 0.9937) with a low detection limit of 1.8 μM (S/N = 3) and a high sensitivity of 1997 μA/mM∙cm−2. It also exhibited good reproducibility as well as high selectivity.http://www.mdpi.com/1424-8220/16/11/1791nonenzymaticglucosegraphenebiosensorin situ
collection DOAJ
language English
format Article
sources DOAJ
author Xiaohui Zhang
Zheng Zhang
Qingliang Liao
Shuo Liu
Zhuo Kang
Yue Zhang
spellingShingle Xiaohui Zhang
Zheng Zhang
Qingliang Liao
Shuo Liu
Zhuo Kang
Yue Zhang
Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
Sensors
nonenzymatic
glucose
graphene
biosensor
in situ
author_facet Xiaohui Zhang
Zheng Zhang
Qingliang Liao
Shuo Liu
Zhuo Kang
Yue Zhang
author_sort Xiaohui Zhang
title Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
title_short Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
title_full Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
title_fullStr Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
title_full_unstemmed Nonenzymatic Glucose Sensor Based on In Situ Reduction of Ni/NiO-Graphene Nanocomposite
title_sort nonenzymatic glucose sensor based on in situ reduction of ni/nio-graphene nanocomposite
publisher MDPI AG
series Sensors
issn 1424-8220
publishDate 2016-10-01
description Ni/NiO nanoflower modified reduced graphene oxide (rGO) nanocomposite (Ni/NiO-rGO) was introduced to screen printed electrode (SPE) for the construction of a nonenzymatic electrochemical glucose biosensor. The Ni/NiO-rGO nanocomposite was synthesized by an in situ reduction process. Graphene oxide (GO) hybrid Nafion sheets first chemical adsorbed Ni ions and assembled on the SPE. Subsequently, GO and Ni ions were reduced by hydrazine hydrate. The electrochemical properties of such a Ni/NiO-rGO modified SPE were carefully investigated. It showed a high activity for electrocatalytic oxidation of glucose in alkaline medium. The proposed nonenzymatic sensor can be utilized for quantification of glucose with a wide linear range from 29.9 μM to 6.44 mM (R = 0.9937) with a low detection limit of 1.8 μM (S/N = 3) and a high sensitivity of 1997 μA/mM∙cm−2. It also exhibited good reproducibility as well as high selectivity.
topic nonenzymatic
glucose
graphene
biosensor
in situ
url http://www.mdpi.com/1424-8220/16/11/1791
work_keys_str_mv AT xiaohuizhang nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
AT zhengzhang nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
AT qingliangliao nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
AT shuoliu nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
AT zhuokang nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
AT yuezhang nonenzymaticglucosesensorbasedoninsitureductionofniniographenenanocomposite
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