Fragmentation of Chitosan by Acids

Fragmentation of Chitosan by Acids

Fragmentation of chitosan in aqueous solution by hydrochloric acid was investigated. The kinetics of fragmentation, the number of chain scissions, and polydispersity of the fragments were followed by viscometry and size exclusion chromatography. The chemical structure and the degree of N-acetylation...

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Main Authors: Mohammad Reza Kasaai, Joseph Arul, Gérard Charlet
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/508540
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spelling doaj-4c6bf13548154418bc2d1086a012245b2020-11-25T02:43:26ZengHindawi LimitedThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/508540508540Fragmentation of Chitosan by AcidsMohammad Reza Kasaai0Joseph Arul1Gérard Charlet2Faculty of Agricultural Engineering, Sari Agricultural Sciences and Natural Resources University, Khazar Abad Road, Km. 9, P.O. Box 578, Sari, Mazandaran, IranDepartment of Food Science and Nutrition, Université Laval, Sainte-Foy, Quebec, QC, G1K 7P4, CanadaDepartment of Chemistry, Université Laval, Sainte-Foy, Quebec, QC, G1K 7P4, CanadaFragmentation of chitosan in aqueous solution by hydrochloric acid was investigated. The kinetics of fragmentation, the number of chain scissions, and polydispersity of the fragments were followed by viscometry and size exclusion chromatography. The chemical structure and the degree of N-acetylation (DA) of the original chitosan and its fragments were examined by 1H NMR spectroscopy and elemental analysis. The kinetic data indicates that the reaction was of first order. The results of polydispersity and the DA suggest that the selected experimental conditions (temperature and concentration of acid) were appropriate to obtain the fragments having the polydispersity and the DA similar to or slightly different from those of the original one. A procedure to estimate molecular weight of fragments as well as the number of chain scissions of the fragments under the experimental conditions was also proposed.http://dx.doi.org/10.1155/2013/508540
collection DOAJ
language English
format Article
sources DOAJ
author Mohammad Reza Kasaai
Joseph Arul
Gérard Charlet
spellingShingle Mohammad Reza Kasaai
Joseph Arul
Gérard Charlet
Fragmentation of Chitosan by Acids
The Scientific World Journal
author_facet Mohammad Reza Kasaai
Joseph Arul
Gérard Charlet
author_sort Mohammad Reza Kasaai
title Fragmentation of Chitosan by Acids
title_short Fragmentation of Chitosan by Acids
title_full Fragmentation of Chitosan by Acids
title_fullStr Fragmentation of Chitosan by Acids
title_full_unstemmed Fragmentation of Chitosan by Acids
title_sort fragmentation of chitosan by acids
publisher Hindawi Limited
series The Scientific World Journal
issn 1537-744X
publishDate 2013-01-01
description Fragmentation of chitosan in aqueous solution by hydrochloric acid was investigated. The kinetics of fragmentation, the number of chain scissions, and polydispersity of the fragments were followed by viscometry and size exclusion chromatography. The chemical structure and the degree of N-acetylation (DA) of the original chitosan and its fragments were examined by 1H NMR spectroscopy and elemental analysis. The kinetic data indicates that the reaction was of first order. The results of polydispersity and the DA suggest that the selected experimental conditions (temperature and concentration of acid) were appropriate to obtain the fragments having the polydispersity and the DA similar to or slightly different from those of the original one. A procedure to estimate molecular weight of fragments as well as the number of chain scissions of the fragments under the experimental conditions was also proposed.
url http://dx.doi.org/10.1155/2013/508540
work_keys_str_mv AT mohammadrezakasaai fragmentationofchitosanbyacids
AT josepharul fragmentationofchitosanbyacids
AT gerardcharlet fragmentationofchitosanbyacids
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