Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats

Dysregulation of Glucose Homeostasis Following Chronic Exogenous Administration of Leptin in Healthy Sprague-Dawley Rats

Introduction: Impaired glucose utilization is seen in chronic hyperleptinaemia associated conditions such as obesity and type 2 diabetes mellitus. It is unclear if this impaired glucose utilization is due to the effect of persistent hyperleptinaemia on insulin secretion from the beta cells of pan...

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Bibliographic Details
Main Authors: Khalil Wjidan, Effendi Ibrahim, Brinnell Caszo, Justin Gnanou, Harbindarjeet Singh
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-12-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
glut 4
glucose homeostasis
hyperinsulinaemia
hyperleptinaemia
insulin receptor
Online Access:https://jcdr.net/articles/PDF/7003/15594_CE(RA1)_F(T)_PF1(Vsu_Om)_PFA(AK)_PF2(PAG).pdf

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https://jcdr.net/articles/PDF/7003/15594_CE(RA1)_F(T)_PF1(Vsu_Om)_PFA(AK)_PF2(PAG).pdf

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