Clinical trial perspective for adult and juvenile Huntington′s disease using genetically-engineered mesenchymal stem cells

Clinical trial perspective for adult and juvenile Huntington′s disease using genetically-engineered mesenchymal stem cells

Progress to date from our group and others indicate that using genetically-engineered mesenchymal stem cells (MSC) to secrete brain-derived neurotrophic factor (BDNF) supports our plan to submit an Investigational New Drug application to the Food and Drug Administration for the future planned Phase...

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Bibliographic Details
Main Authors: Peter Deng, Audrey Torrest, Kari Pollock, Heather Dahlenburg, Geralyn Annett, Jan A Nolta, Kyle D Fink
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
mesenchymal stem cells; neurodegenerative disorders
Huntington′s disease; genetic engineering; brain derived neurotrophic factor
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=5;spage=702;epage=705;aulast=Deng

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