Separation of breast cancer and organ microenvironment transcriptomes in metastases

Separation of breast cancer and organ microenvironment transcriptomes in metastases

Abstract Background The seed and soil hypothesis was proposed over a century ago to describe why cancer cells (seeds) grow in certain organs (soil). Since then, the genetic properties that define the cancer cells have been heavily investigated; however, genomic mediators within the organ microenviro...

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Bibliographic Details
Main Authors: Mohammad A. Alzubi, Tia H. Turner, Amy L. Olex, Sahib S. Sohal, Nicholas P. Tobin, Susana G. Recio, Jonas Bergh, Thomas Hatschek, Joel S. Parker, Carol A. Sartorius, Charles M. Perou, Mikhail G. Dozmorov, J. Chuck Harrell
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Luciferase
Metastasis
Microenvironment
Patient-derived xenograft
RNA sequencing
Online Access:http://link.springer.com/article/10.1186/s13058-019-1123-2

Internet

http://link.springer.com/article/10.1186/s13058-019-1123-2

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