Dextromethorphan Dampens Neonatal Astrocyte Activation and Endoplasmic Reticulum Stress Induced by Prenatal Exposure to Buprenorphine

Dextromethorphan Dampens Neonatal Astrocyte Activation and Endoplasmic Reticulum Stress Induced by Prenatal Exposure to Buprenorphine

Prenatal exposure to buprenorphine renders offspring vulnerable to cerebral impairments. In this study, our data demonstrate, for the first time, that prenatal exposure to buprenorphine escalates astrocyte activation concurrent with indications of endoplasmic reticulum (ER) stress in the hippocampi...

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Bibliographic Details
Main Authors:	Chun-Hua Lin, Pao-Luh Tao, Huey-Jen Tsay, Yao-Chang Chiang, Wei-Tang Chang, Ing-Kang Ho, Feng-Shiun Shie
Format:	Article
Language:	English
Published:	Hindawi Limited 2021-01-01
Series:	Behavioural Neurology
Online Access:	http://dx.doi.org/10.1155/2021/6301458

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