Mice lacking the SLAM family member CD84 display unaltered platelet function in hemostasis and thrombosis.

Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity by forming thrombi at sites of vascular injury. Although the early events of thrombus formation--platelet adhesion and aggregation--have been intensively studied, less is known about the m...

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Bibliographic Details
Main Authors: Sebastian Hofmann, Attila Braun, Rastislav Pozgaj, Martina Morowski, Timo Vögtle, Bernhard Nieswandt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4281120?pdf=render