Changes in the transcriptome of the prefrontal cortex of OXYS rats as the signs of Alzheimer’s disease development
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease. It produces atrophic changes in the brain, which cause dementia. The incidence of AD is increasing with increasing life expectancy and gradual aging of the population in developed countries. There are no effective prophylacti...
Main Authors: | N. A. Stefanova, E. E. Korbolina, N. I. Ershov, E. I. Rogaev, N. G. Kolosova |
---|---|
Format: | Article |
Language: | English |
Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2015-12-01
|
Series: | Vavilovskij Žurnal Genetiki i Selekcii |
Subjects: | |
Online Access: | https://vavilov.elpub.ru/jour/article/view/434 |
Similar Items
-
Association of cerebrovascular dysfunction with the development of Alzheimer’s disease-like pathology in OXYS rats
by: Natalia A. Stefanova, et al.
Published: (2018-02-01) -
SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats
by: Natalia A. Muraleva, et al.
Published: (2020-07-01) -
Mechanisms of Neuronal Death in the Cerebral Cortex during Aging and Development of Alzheimer’s Disease-Like Pathology in Rats
by: Darya V. Telegina, et al.
Published: (2019-11-01) -
COMPARISON OF THE COMPLETE NUCLEOTIDE SEQUENCES OF MITOCHONDRIAL DNA FROM WISTAR AND OXYS RAT STRAINS MAINTAINED AT THE INSTITUTE OF CYTOLOGY AND GENETICS SB RAS
by: R. A. Maksyutov, et al.
Published: (2015-01-01) -
MEK1/2-ERK Pathway Alterations as a Therapeutic Target in Sporadic Alzheimer’s Disease: A Study in Senescence-Accelerated OXYS Rats
by: Natalia A. Muraleva, et al.
Published: (2021-06-01)