miR-325-3p, a novel regulator of osteoclastogenesis in osteolysis of colorectal cancer through targeting S100A4

miR-325-3p, a novel regulator of osteoclastogenesis in osteolysis of colorectal cancer through targeting S100A4

Abstract Background To investigate effect of microRNA-325-3p (miR-325-3p) on bone metastasis of colorectal cancer (CRC) and the precise role on osteoclastogenesis. Methods CT-26 cells were injected into tibias to establish bone metastatic model of CRC in vivo. AgomiR-325-3p or antagomir-325-3p were...

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Bibliographic Details
Main Authors: Li Chengling, Zhang Yulin, Xie Xiaoyu, Lu Xingchen, Zhang Sen, Wang Ziming, Chen Xianming
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Molecular Medicine
Subjects:
miR-325-3p
Bone metastasis
Colorectal cancer cells
S100A4
Online Access:https://doi.org/10.1186/s10020-021-00282-7

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