Anti-CCL21 Antibody Attenuates Infarct Size and Improves Cardiac Remodeling After Myocardial Infarction

Anti-CCL21 Antibody Attenuates Infarct Size and Improves Cardiac Remodeling After Myocardial Infarction

Background/Aims: Over-activation of cellular inflammatory effectors adversely affects myocardial function after acute myocardial infarction (AMI). The CC-chemokine CCL21 is, via its receptor CCR7, one of the key regulators of inflammation and immune cell recruitment, participates in various inflamma...

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Bibliographic Details
Main Authors: Yi Jiang, Jianwen Bai, Lunxian Tang, Pei Zhang, Jun Pu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Inflammatory response
Cardiac remodeling
CCL21
Myocardial infarction
Online Access:http://www.karger.com/Article/FullText/430224

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