Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism.

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism.

Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular occlusive diseases. Phenotypically modulated smooth m...

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Bibliographic Details
Main Authors: Feng Shi, Xiaochun Long, Allison Hendershot, Joseph M Miano, Jane Sottile
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994013?pdf=render

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