Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection
Following infection with Leishmania major, T cell activation and apoptosis can be detected in draining lymph nodes of C57BL/6-infected mice. We investigated the mechanisms involved in apoptosis and cytokine expression following Tcellactivation. After two weeks of infection, apoptotic T cells were no...
Main Authors: | Wânia F. Pereira, Landi V.C. Guillermo, Flávia L. Ribeiro-Gomes, Marcela F. Lopes |
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Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Ciências
2008-03-01
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Series: | Anais da Academia Brasileira de Ciências |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000100008 |
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