Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development

Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development

The derivation of human pluripotent stem cell (iPSC) lines by in vitro reprogramming of somatic cells revolutionized research: iPSCs have been used for disease modeling, drug screening and regenerative medicine for many disorders, especially when combined with cutting-edge genome editing technologie...

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Bibliographic Details
Main Authors: A. Donada, F. Basso-Valentina, B. Arkoun, B. Monte-Mor, I. Plo, H. Raslova
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Subjects:
iPSCs
Hematological malignancies
Drug screen
Differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120303615

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