Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

The widely used animal models for tuberculosis (TB) display fundamental differences from human TB. Therefore, a validated model that recapitulates human lung TB is attractive for TB research. Here, we describe a unique method for establishment of TB infection in an experimental human lung tissue mod...

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Bibliographic Details
Main Authors: Venkata Ramanarao Parasa, Muhammad Jubayer Rahman, Anh Thu Ngyuen Hoang, Mattias Svensson, Susanna Brighenti, Maria Lerm
Format: Article
Language:English
Published: The Company of Biologists 2014-02-01
Series:Disease Models & Mechanisms
Subjects:
Tuberculosis
M. tuberculosis
Granuloma
In vitro model
Lung tissue
ESX-1
Online Access:http://dmm.biologists.org/content/7/2/281

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