Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer.

Liver infection is an obligatory step in malarial transmission, but it remains unclear how the sporozoites gain access to the hepatocytes, which are separated from the circulatory system by the liver sinusoidal cell layer. We found that a novel microneme protein, named sporozoite microneme protein e...

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Bibliographic Details
Main Authors: Tomoko Ishino, Kazuhiko Yano, Yasuo Chinzei, Masao Yuda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC314464?pdf=render