Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy: part I1

This is the first of a series of reviews of the controversy that swirled around the “lipid hypothesis” of atherosclerosis for so many years. Today, in the era of the statins, there is no longer any doubt about the value of decreasing blood cholesterol levels. In fact, “the lower the better” is the p...

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Bibliographic Details
Main Author: Daniel Steinberg
Format: Article
Language:English
Published: Elsevier 2004-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520312748
Description
Summary:This is the first of a series of reviews of the controversy that swirled around the “lipid hypothesis” of atherosclerosis for so many years. Today, in the era of the statins, there is no longer any doubt about the value of decreasing blood cholesterol levels. In fact, “the lower the better” is the position of many clinicians. However, getting to this point has been a long uphill battle marked by heated debate and sometimes violent disagreement.The history of this controversy is worth telling for its own sake and because remembering it may help us avoid similar mistakes in the future.
ISSN:0022-2275