The absence of plasma free fatty acid response to epinephrine in vitamin-C-deprived guinea pigs
Plasma concentrations of free fatty acid (FFA) and blood glucose were measured in normal and 25-day scorbutic guinea pigs 15 minutes after injection of either saline or epinephrine. The normal group showed a large increase in FFA after epinephrine and a smaller increase after saline as compared to n...
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| Format: | Article |
| Language: | English |
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Elsevier
1962-01-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520404559 |
| Summary: | Plasma concentrations of free fatty acid (FFA) and blood glucose were measured in normal and 25-day scorbutic guinea pigs 15 minutes after injection of either saline or epinephrine. The normal group showed a large increase in FFA after epinephrine and a smaller increase after saline as compared to no injection at all. The scorbutic animals had no increase of FFA either after saline or epinephrine. The injection of 50 mg ascorbic acid intraperitoneally into 25-day scorbutic guinea pigs 5 hours before sacrifice restored to this group the normal response to epinephrine and saline. The mean plasma 17-OH corticosteroid concentration was 206.5 μg/100 ml for six 25-day scorbutic guinea pigs and was 71.5 μg/100 ml for six normal guinea pigs. Scorbutic animals had marked increases of glucose both after saline and epinephrine injections as compared to uninjected scorbutic animals. |
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| ISSN: | 0022-2275 |