RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes

RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes

We developed a single vector recombinant adeno-associated viral (rAAV) expression system for spatial and reversible control of polycistronic gene expression. Our approach (i) integrates the advantages of the tetracycline (Tet)-controlled transcriptional silencer tTSKid and the self-cleaving 2A pepti...

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Bibliographic Details
Main Authors:	Yiwei Chen, Liji Cao, Chonglin Luo, Désirée AW Ditzel, Jörg Peter, Rolf Sprengel
Format:	Article
Language:	English
Published:	Elsevier 2013-01-01
Series:	Molecular Therapy: Nucleic Acids
Subjects:	2A peptide bridge conditional gene expression rAAV Tet system
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253116301469

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