Polymorphisms in autophagy genes and active pulmonary tuberculosis susceptibility in Romania

Polymorphisms in autophagy genes and active pulmonary tuberculosis susceptibility in Romania

Autophagy, a homeostatic process involved in nutrient regeneration and immune responses, may be involved in intracellular killing of M. tuberculosis. Several studies linked variation in autophagy genes with susceptibility to pulmonary tuberculosis, but others did not confirm these findings.

Bibliographic Details
Main Authors: Cucu Mihai Gabriel, Streața Ioana, Riza Anca Lelia, Cimpoeru Alina Liliana, Șerban-Șoșoi Simona, Ciocoiu Adela, Pleșea Răzvan Mihail, Popescu Elena Leocadia, Dorobanțu Ștefania, Anghel Andreea, Stroe Aida Maria, Ștefan Andreea Nicoleta, Cioboată Ramona, Băzăvan Ileana, Ciontea Marius Sorin, Căpitănescu Iulia, Olteanu Mihai, Nițu Mimi, Burada Florin, Tătaru Tiberiu, Netea Mihai, van Crevel Reinout, Olaru Marian, Mixich Francisc, Ioana Mihai
Format: Article
Language:English
Published: Sciendo 2017-03-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
tuberculosis
gene polymorphism
autophagy
innate immune system
allele
Online Access:https://doi.org/10.1515/rrlm-2017-0002

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