The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy

The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy

One of the hallmarks of placental dysfunction is the increase of oxidative stress. This process, along with the overexpression of the inflammasome, creates a downward spiral that can lead to a series of severe pregnancy complications. Ferroptosis is a form of iron-mediated cell death involving the a...

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Bibliographic Details
Main Authors: Li Meihe, Gao Shan, Kang Minchao, Wu Xiaoling, An Peng, Wu Xili, Zheng Jin, Dang Huimin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ferroptosis
HTR-8/SVneo
oxidative stress
NLRP1 inflammasome
pathological pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.707959/full

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