Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R

Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R

Abstract Neuroendocrine tumors may present with pseudoallergic reactions like diarrhea and idiopathic anaphylaxis. Here we present the P-STS human ileal neuroendocrine cell line as a model cell line for these tumors. Neuroendocrine markers and changes in cytoplasmic calcium concentration ([Ca2+]i) i...

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Bibliographic Details
Main Authors:	Beatrix Pfanzagl, Diana Mechtcheriakova, Anastasia Meshcheryakova, Stephan W. Aberle, Roswitha Pfragner, Erika Jensen-Jarolim
Format:	Article
Language:	English
Published:	Nature Publishing Group 2017-05-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-01453-5

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