A spheroid-based 3-D culture model for pancreatic cancer drug testing, using the acid phosphatase assay
Current therapy for pancreatic cancer is multimodal, involving surgery and chemotherapy. However, development of pancreatic cancer therapies requires a thorough evaluation of drug efficacy in vitro before animal testing and subsequent clinical trials. Compared to two-dimensional cultu...
Main Authors: | Z. Wen, Q. Liao, Y. Hu, L. You, L. Zhou, Y. Zhao |
---|---|
Format: | Article |
Language: | English |
Published: |
Associação Brasileira de Divulgação Científica
2013-08-01
|
Series: | Brazilian Journal of Medical and Biological Research |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700634&lng=en&tlng=en |
Similar Items
-
3D-tips: user-friendly mesh barrier pipette tips for 3D-spheroid culture
by: Mo Chen, et al.
Published: (2019-10-01) -
Recent Advances in Three-Dimensional Multicellular Spheroid Culture and Future Development
by: Honglin Shen, et al.
Published: (2021-01-01) -
Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells
by: Omidreza Firuzi, et al.
Published: (2019-05-01) -
E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity
by: I. Smyrek, et al.
Published: (2019-01-01) -
Natural and Synthetic Biomaterials for Engineering Multicellular Tumor Spheroids
by: Advika Kamatar, et al.
Published: (2020-10-01)