Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis

Cerebral blood flow and cerebrovascular reactivity are preserved in a mouse model of cerebral microvascular amyloidosis

Impaired cerebrovascular function is an early biomarker for cerebral amyloid angiopathy (CAA), a neurovascular disease characterized by amyloid-β accumulation in the cerebral vasculature, leading to stroke and dementia. The transgenic Swedish Dutch Iowa (Tg-SwDI) mouse model develops cerebral microv...

Full description

Bibliographic Details
Main Authors:	Leon P Munting, Marc Derieppe, Ernst Suidgeest, Lydiane Hirschler, Matthias JP van Osch, Baudouin Denis de Senneville, Louise van der Weerd
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2021-02-01
Series:	eLife
Subjects:	cerebral amyloid angiopathy cerebrovascular function arterial spin labeling-MRI
Online Access:	https://elifesciences.org/articles/61279

Similar Items

Predicting cerebral amyloid angiopathy-realated intracerebral hemorrhages and other cerebrovascular disorders in Alzheimer’s disease
by: Masahito eYamada
Published: (2012-04-01)

Cerebral Amyloid Angiopathy: Emerging Concepts
by: Masahito Yamada
Published: (2015-01-01)

The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy
by: Alan W. J. Morris, et al.
Published: (2014-09-01)

Cerebral Microbleeds
by: Çağla
Published: (2019-12-01)

Regional Cerebral Perfusion and Cerebrovascular Reactivity in Elderly Controls With Subtle Cognitive Deficits
by: Merel van der Thiel, et al.
Published: (2019-02-01)

Undiagnosed senile systemic amyloidosis with mesenteric angiopathy leading to fatal outcomes: Two case series with a review of literature
by: Avneesh Gupta, et al.
Published: (2017-01-01)

CEREBRAL AMYLOID ANGIOPATHY
by: Dan Popescu, et al.
Published: (2010-06-01)

Robust neuroinflammation and perivascular pathology in rTg-DI rats, a novel model of microvascular cerebral amyloid angiopathy
by: Xiaoyue Zhu, et al.
Published: (2020-03-01)

CD40L disruption enhances Aβ vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation
by: D. Obregon, et al.
Published: (2008-02-01)

Histological and immunohistochemical characteristics of cerebral amyloid angiopathy in elderly dogs
by: Slađan Nešić, et al.
Published: (2017-01-01)

Cerebral microbleeds: Spatial distribution implications
by: Loehrer Elizabeth, et al.
Published: (2014-06-01)

Cerebral amyloid angiopathy-related inflammation (CAARI): case report
by: Karol Adam Makarewicz, et al.
Published: (2019-06-01)

Brain Transcriptomic Analysis of Hereditary Cerebral Hemorrhage With Amyloidosis-Dutch Type
by: Laure Grand Moursel, et al.
Published: (2018-04-01)

Advances of cerebral amyloid angiopathy and related cognitive impairment
by: Zhen ZHEN, et al.
Published: (2019-08-01)

Sporadic cerebral amyloid angiopathy: An important cause of cerebral hemorrhage in the elderly
by: Shahina Bano, et al.
Published: (2011-01-01)

Intracerebral Hemorrhage Recurrence in Patients with and without Cerebral Amyloid Angiopathy
by: João Pinho, et al.
Published: (2021-01-01)

Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy
by: Han Byung, et al.
Published: (2011-12-01)

Cerebral amyloid angiopathy: A clinicopathological study of three cases
by: Panicker Jalesh, et al.
Published: (2010-01-01)

Exercise Training Increases Parietal Lobe Cerebral Blood Flow in Chronic Stroke: An Observational Study
by: Andrew D. Robertson, et al.
Published: (2017-09-01)

Decreased Basal Ganglia Volume in Cerebral Amyloid Angiopathy
by: Panagiotis Fotiadis, et al.
Published: (2021-05-01)

Prognostic significance of atraumatic convexal subarachnoid hemorrhage in patients with cerebral amyloid angiopathy
by: Özlem Aykaç, et al.
Published: (2020-08-01)

A Case of Possible Cerebral Amyloid Angiopathy Presenting with Diffuse Cerebellar Hemosiderosis
by: Selen Gür Özmen, et al.
Published: (2013-09-01)

Cerebral Amyloid Angiopathy: A Case Report and Literature ...
by: Orkide Kutlu, et al.
Published: (2015-03-01)

Recurrent Subarachnoid Bleeding and Superficial Siderosis in a Patient with Histopathologically Proven Cerebral Amyloid Angiopathy
by: P. Profice, et al.
Published: (2011-05-01)

Cerebral Amyloid Angiopathy Presenting with Synchronous Bilateral Intracerebral Macrohemorrhages
by: Jeremy S. Shelton, et al.
Published: (2015-11-01)

Sex differences in a murine model of Cerebral Amyloid Angiopathy
by: Michael E. Maniskas, et al.
Published: (2021-07-01)

Analysis on two cases of cerebral amyloid angiopathy-related inflammation
by: Dong-yang HU, et al.
Published: (2019-01-01)

The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets
by: Xue-mei Qi, et al.
Published: (2017-08-01)

Cerebral Amyloid Angiopathy Related Inflammation With Prominent Meningeal Involvement. A Report of 2 Cases
by: Agnès Aghetti, et al.
Published: (2019-09-01)

Non-inflammatory cerebral amyloid angiopathy as a cause of rapidly progressive dementia: A case study
by: Leonel Tadao Takada, et al.

The microvascular extracellular matrix in brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)
by: Mamatha Damodarasamy, et al.
Published: (2020-09-01)

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy
by: Laura Gatti, et al.
Published: (2020-05-01)

Longitudinal decrease in blood oxygenation level dependent response in cerebral amyloid angiopathy
by: Aaron R. Switzer, et al.
Published: (2016-01-01)

Recurrent craniospinal subarachnoid hemorrhage in cerebral amyloid angiopathy
by: Mathew Alexander, et al.
Published: (2013-01-01)

Proteomics analysis identifies new markers associated with capillary cerebral amyloid angiopathy in Alzheimer’s disease
by: David C. Hondius, et al.
Published: (2018-06-01)

Intracerebral hemorrhage in the context of cerebral amyloid angiopathy and varied time of onset of cerebral venous thrombosis: a case report
by: Tadeusz A. Mendel, et al.
Published: (2017-09-01)

Cerebral Amyloid Angiopathy
by: Mahmut Edip Gürol
Published: (2009-03-01)

Brain insulin signaling and cerebrovascular disease in human postmortem brain
by: Zoe Arvanitakis, et al.
Published: (2021-04-01)

Multiple intracranial hemorrhages in a normotensive demented patient: A probable cerebral amyloid angiopathy
by: Ahmad Chitsaz, et al.
Published: (2012-01-01)

10-Year Follow-Up of a Patient with Cerebral Amyloid Angiopathy
by: Min Kyoung Kang, et al.
Published: (2020-12-01)