Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum

Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum

Differentiation-inducing factor-3 (DIF-3), found in the cellular slime mold Dictyostelium discoideum, and its derivatives, such as butoxy-DIF-3 (Bu-DIF-3), are potent anti-tumor agents. To investigate the activity of DIF-like molecules in tumor cells, we recently synthesized a green fluorescent DIF-...

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Bibliographic Details
Main Authors: Yuzuru Kubohara, Haruhisa Kikuchi, Yusuke Matsuo, Yoshiteru Oshima, Yoshimi Homma
Format: Article
Language:English
Published: The Company of Biologists 2014-03-01
Series:Biology Open
Subjects:
Dictyostelium discoideum
DIF
Anti-tumor agent
Mitochondria
Uncoupler
Online Access:http://bio.biologists.org/content/3/4/289

Internet

http://bio.biologists.org/content/3/4/289

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