AKT inhibitor suppresses hyperthermia-induced Ndrg2 phosphorylation in gastric cancer cells

Hyperthermia is one of the most effective adjuvant treatments for various cancers with few side effects. However, the underlying molecular mechanisms still are not known. N-myc downstream-regulated gene 2 (NDRG2), a tumor suppressor, has been shown to be involved in diverse cellular stresses includi...

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Bibliographic Details
Main Authors: Yurong Tao, Yan Guo, Wenchao Liu, Jian Zhang, Xia Li, Lan Shen, Yi Ru, Yan Xue, Jin Zheng, Xinping Liu, Jing Zhang, Libo Yao
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000400394&lng=en&tlng=en