Immunodeficient Rabbit Models: History, Current Status and Future Perspectives

Immunodeficient Rabbit Models: History, Current Status and Future Perspectives

Production of immunodeficient (ID) models in non-murine animal species had been extremely challenging until the advent of gene-editing tools: first zinc finger nuclease (ZFN), then transcription activator-like effector nuclease (TALEN), and most recently clustered regularly interspaced short palindr...

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Bibliographic Details
Main Authors: Jun Song, Brooke Pallas, Dongshan Yang, Jifeng Zhang, Yash Agarwal, Y. Eugene Chen, Moses Bility, Jie Xu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Applied Sciences
Subjects:
immunodeficient rabbits
gene editing
animal models
Online Access:https://www.mdpi.com/2076-3417/10/20/7369

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