B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis

B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis

Interaction between B and CD4 T cells is crucial for their optimal responses in adaptive immunity. Immune responses augmented by their partnership promote chronic inflammation. Here we report that interaction between B and CD4 T cells augments their atherogenicity to promote lipid-induced atheroscle...

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Bibliographic Details
Main Authors: Christopher Tay, Peter Kanellakis, Hamid Hosseini, Anh Cao, Ban-Hock Toh, Alex Bobik, Tin Kyaw
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
atherosclerosis
B cells
CD4 T cells
MHCII
CD40
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03046/full

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