Cancer Patient T Cells Genetically Targeted to Prostate-Specific Membrane Antigen Specifically Lyse Prostate Cancer Cells and Release Cytokines in Response to Prostate-Specific Membrane Antigen

The expression of immunoglobulin-based artificial receptors in normal T lymphocytes provides a means to target lymphocytes to cell surface antigens independently of major histocompatibility complex restriction. Such artificial receptors have been previously shown to confer antigen-specific tumorici...

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Bibliographic Details
Main Authors: Michael C. Gong, Jean-Baptiste Latouche, Anja Krause, Warren D.W. Heston, Neil H. Bander, Michel Sadelain
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800529