Systemic panca-associated vasculitis with central nervous involvement causing recurrent myelitis: case report

<p>Abstract</p> <p>Background</p> <p>We report on the case of an established perinuclear antineutrophil cytoplasmic antibody (pANCA) associated renal vasculitis being treated with prednisolone and rituximab, where the patient presented with leg weakness, urinary and fae...

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Bibliographic Details
Main Authors: Bull Matthew D, Whitehead Duncan J, Hamilton Alexander J, D'Souza Richard J
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/10/118
Description
Summary:<p>Abstract</p> <p>Background</p> <p>We report on the case of an established perinuclear antineutrophil cytoplasmic antibody (pANCA) associated renal vasculitis being treated with prednisolone and rituximab, where the patient presented with leg weakness, urinary and faecal incontinence and buttock pain consistent with transverse myelitis.</p> <p>Case presentation</p> <p>The patient underwent MRI scanning showing patchy cord enhancement from T10 to the conus, which was suggestive of a cord malignancy. Prior to a cord biopsy, he was treated with steroids and a repeat MRI showed resolution of the original lesion with a new similar lesion from C7 to T3.</p> <p>Conclusions</p> <p>He made a marked recovery after further treatment with high dose steroids and plasma exchange.</p>
ISSN:1471-2377