Developing Novel Host-Based Therapies Targeting Microbicidal Responses in Macrophages and Neutrophils to Combat Bacterial Antimicrobial Resistance

Developing Novel Host-Based Therapies Targeting Microbicidal Responses in Macrophages and Neutrophils to Combat Bacterial Antimicrobial Resistance

Antimicrobial therapy has provided the main component of chemotherapy against bacterial pathogens. The effectiveness of this strategy has, however, been increasingly challenged by the emergence of antimicrobial resistance which now threatens the sustained utility of this approach. Humans and animals...

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Bibliographic Details
Main Authors: Katie Watson, Clark D. Russell, J. Kenneth Baillie, Kev Dhaliwal, J. Ross Fitzgerald, Timothy J. Mitchell, A. John Simpson, Stephen A. Renshaw, David H. Dockrell
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
antimicrobial resistance
macrophage
neutrophil
host-based therapies
innate immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00786/full

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