Editing DNA Methylation in Mammalian Embryos

Editing DNA Methylation in Mammalian Embryos

DNA methylation in mammals is essential for numerous biological functions, such as ensuring chromosomal stability, genomic imprinting, and X-chromosome inactivation through transcriptional regulation. Gene knockout of DNA methyltransferases and demethylation enzymes has made significant contribution...

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Bibliographic Details
Main Authors:	Taiga Yamazaki, Yu Hatano, Ryoya Taniguchi, Noritada Kobayashi, Kazuo Yamagata
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	International Journal of Molecular Sciences
Subjects:	dna methylation epigenome editing preimplantation embryo germ cell centromere pericentromere
Online Access:	https://www.mdpi.com/1422-0067/21/2/637

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