Nucleosome dynamics: HMGB1 facilitates nucleosome restructuring and collaborates in estrogen-responsive gene expression
The genome in the human cell is extraordinarily compacted in the nucleus. As a result, much of the DNA is inaccessible and functionally inert. Notwithstanding the highly efficient packaging, mechanisms have evolved to render DNA sites accessible that then enable a multitude of factors to carry out o...
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| Format: | Article |
| Language: | English |
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AIMS Press
2016-12-01
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| Series: | AIMS Genetics |
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| Online Access: | http://www.aimspress.com/Genetics/article/1136/fulltext.html |