Association of TLR4-T399I Polymorphism with Chronic Obstructive Pulmonary Disease in Smokers

Tobacco smoking has been considered the most important risk factor for chronic obstructive pulmonary disease (COPD) development. However, not all smokers develop COPD and other environmental and genetic susceptibility factors underlie disease pathogenesis. Recent studies have indicated that the impa...

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Bibliographic Details
Main Authors: Matthaios Speletas, Vassiliki Merentiti, Konstantinos Kostikas, Kyriaki Liadaki, Markos Minas, Konstantinos Gourgoulianis, Anastasios E. Germenis
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2009/260286