Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

Pathophysiology of Blood–Brain Barrier Permeability Throughout the Different Stages of Ischemic Stroke and Its Implication on Hemorrhagic Transformation and Recovery

The blood–brain barrier (BBB) is a dynamic interface responsible for maintaining the central nervous system homeostasis. Its unique characteristics allow protecting the brain from unwanted compounds, but its impairment is involved in a vast number of pathological conditions. Disruption of the BBB an...

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Bibliographic Details
Main Authors: Sara Bernardo-Castro, João André Sousa, Ana Brás, Carla Cecília, Bruno Rodrigues, Luciano Almendra, Cristina Machado, Gustavo Santo, Fernando Silva, Lino Ferreira, Isabel Santana, João Sargento-Freitas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Neurology
Subjects:
blood-brain barrier
permeability
stroke
hemorrhagic transformation
pathophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.594672/full

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